Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

Personal Website

PD Dr.-Ing. Kuangyu Shi

Kuangyu Shi
PD Dr.-ing Kuangyu Shi
Senior Scientist Head of Lab for Artificial Intelligence & Translational Theranostics
Email:k.shi@tum.de Email:kuangyu.shi@dbmr.unibe.ch
Address: Address:
Chair for Computer Aided Medical Procedures & Augmented Reality
Fakultät für Informatik
Technische Universität München
Boltzmannstr. 3
85748 Garching b. München
Lab for Artificial Intelligence & Translational Theranostics
Dept. Nuclear Medicine
University of Bern
3010 Bern

Research Focus

  • Translational molecular imaging computing
  • Deep learning for computer-aided diagnosis
  • Computational modeling of molecular imaging and tumor microenvironment

Short CV

  • 04/2018 – present
    Lab for Artificial Intelligence & Translational Theranostics Dept. Nuclear Medicine, Inselspital, University of Bern, Switzerland
    • Head of Lab for Artificial Intelligence & Translational Theranostics

  • 04/2018 – present
    Chair for Computer-aided Medical Procedures, Dept. Informatics, Technical University of Munich, Germany
    • Senior scientist

  • 05/2018
    Dept. Informatics, Technical University of Munich, Germany
    • Habilitation

  • 12/2011 – 03/2018
    Dept. Nuclear Medicine, Technical University of Munich, Germany
    • Head of subgroup for translational molecular imaging computing supported by Prof. Sibylle Ziegler and Prof. Markus Schwaiger

  • 12/2008 – 11/2011
    Dept. Radiation Oncology & Dept. Nuclear Medicine, Technical University of Munich, Germany
    • Postdoctoral researcher

  • 02/2005 – 11/2008
    Max-Planck Institute for Computer Science, Saarbrücken, Germany
    • Ph.D in Computer Science, supervised by Prof. Holger Theisel and Prof. Hans-Peter Seidel

  • 10/2003 – 01/2005
    International Max-Planck Research School, Saarbrücken, Germany
    • Master in Computer Science

  • 09/1999 – 07/2003
    Nanjing University, China
    • Bachelor in Computer Science & Bachelor in Physics


WS2018/19, SS2018 Introduction to Artificial Intelligence in Medical Imaging for NonInformatics? Scientists
WS2017/18 Introduction to Informatic I for Engineering Science (with Prof. Bjoern Menze)
SS2009-SS2018 Medical Imaging Technology (with Prof. Sibylle Ziegler)
WS2009/2010-SS2017 Preclinical Imaging (with Prof. Gil Westmeyer and Prof. Sibylle Ziegler)
WS2016/2017 Pharmacokinetics and Metabolism in Molecular Imaging (with PD Dr. Behrooz Yousefi)
SS2014-WS2016/2017 Image-based Biomedical Modeling (with Prof. Bjoern Menze)
SS2016 Computational Physiology for Medical Image Computing (with Prof. Bjoern Menze)
WS2010-WS2012 Computer Aided Medical Procedure I (with Prof. Nassir Navab)


  • T Grimmer†∗, K Shi†∗, J Diehl-Schmid, B Natale, A Drzezga, S Frster, H Frstl, M Schwaiger, I Yakushev, HJ Wester, A Kurz, BH Yousefi. 18F-FIBT may expand PET for -amyloid imaging in neurodegenerative diseases. Mol Psychiatry 2018 Aug 17 († Equal contribution)

  • L. Xu, G. Tetteh, J. Lipkova, Y. Zhao, H. Li, P. Christ, M. Piraud, A. Buck, K. Shi†∗ and B. H. Menze†. Automated Whole-Body Bone Lesion Detection for Multiple Myeloma on 68GaPentixafor PET/CT Imaging Using Deep Learning Methods. Contrast Media Mol Imaging, Epub online Jan. 2018 († Equal contribution, * Corresponding author)

  • L Xu, P Vaupel, BH Menze, K Shi. Impact of Temporal Heterogeneity of Acute Hypoxia on the Radiation Response of Experimental Tumors. Adv Exp Med Biol 2018;1072:189-194

  • L. Xu, P. Vaupel, S. Bai, B. H. Menze, K. Shi. Computational Simulation of Tumor Hypoxia Based on in vivo Microvasculature Assessed in a Dorsal Skin Window Chamber. Adv Exp Med Biol 2017;977:109-117

  • K. Shi, C. Bayer, F. Gaertner, S. T. Astner, J.J. Wilkens, F. Nuesslin, P. Vaupel, S. I. Ziegler. Matching the reaction-diffusion simulation to dynamic [18F]FMISO PET measurements in tumors: extension to a flow-limited oxygen-dependent model. Physiol Meas 2017; 38 (2): 188-204

  • K. Shi, S. Fu¨rst, L. Sun, M. Lukas, N. Navab, S. F¨orster, S. I. Ziegler. Individual refinement of attenuation correction maps for hybrid PET/MR based on multi-resolution regional learning. Comput Med Imaging Graph 2017; in press

  • H. Zhang, P. Wu, S. I. Ziegler, Y. Guan, Y. Wang, J. Ge, M. Schwaiger, S. C. Huang, C. Zuo, S. F¨orster, K Shi. Data-driven Identification of Intensity Normalization Region based on Longitudinal Coherency of 18F-FDG Metabolism in the Healthy Brain. NeuroImage? 2017; 146:589-599

  • Z. Liu, Z. Jian, Q. Wang, T. Cheng, B. Feuerecker, M. Schwaiger, S.-C. Huang, S. I. Ziegler, K. Shi. A Continuously Infused Microfluidic Radioassay System for the Characterization of Cellular Pharmacokinetics. J Nucl Med 2016; 57(10):1548-1555

  • K. Shi, C. Bayer, S. T. Astner, F. C. Gaertner, P. Vaupel, M. Schwaiger, S. C. Huang, S. I. Ziegler. Quantitative Analysis of [18F]FMISO PET for Tumor Hypoxia: Correlation of Modeling Results with Immunohistochemistry. Mol Imaging Biol 2017; 19(1):120-129

  • K. Shi, S. I. Ziegler, P Vaupel. Molecular imaging of tumor hypoxia: Existing problems and their potential model-based solutions. Adv Exp Med Biol 2016; 923:87-93

  • Q. Wang, Z. Liu, S. I. Ziegler, K. Shi. Enhancing spatial resolution of 18F positron imaging with the timepix detector by classification of primary fired pixels using support vector machine. Phys Med Biol 2015; 60(13):5261-5278

  • X. Cheng, Z. Li, Z. Liu, N. Navab, S. C. Huang, U. Keller, S. I. Ziegler, K. Shi. Direct Parametric Image Reconstruction in Reduced Parameter Space for Rapid Multi-Tracer PET Imaging. IEEE Trans Med Imaging 2015; 34(7):1498-1512

  • Q. Wang, P. Vaupel, S. I. Ziegler, K. Shi. Exploring the quantitative relationship between metabolism and enzymatic phenotype by physiological modeling of glucose metabolism and lactate oxidation in solid tumors. Phys Med Biol 2015; 60(6): 2547-2571

  • X. Cheng, C. Bayer, C. A. Maftei, S. T. Astner, P. Vaupel, S. I. Ziegler, K. Shi. Preclinical evaluation of parametric image reconstruction of [18F]FMISO PET: correlation with ex vivo immunohistochemistry. Phys Med Biol 2014;59(2):347-62

  • Q. Wang, J. Tous, Z. Liu, S. I. Ziegler, K. Shi. Evaluation of Timepix Silicon Detector for the Detection of 18F Positrons. J Inst 2014

  • K. Shi, M. Souvatzoglou, S.T. Astner, P. Vaupel, F. Nu¨sslin, J. J. Wilkens, S. I. Ziegler. Quantitative assessment of hypoxia kinetic models by a cross-study of dynamic 18F-FAZA and 15OH2O in patients with head and neck tumors. J Nucl Med, 51(9) 2010

  • K. Shi, H. Theisel, T. Weinkauf, H. C. Hege and H. P. Seidel. Visualizing Transport Structures of Time-dependent Flow Fields. IEEE Computer Graphics and Applications, 28(5), 2008

  • K. Shi, H. Theisel, T. Weinkauf, H. Hauser, H. C. Hege and H.-P. Seidel. Extracting Separation Surfaces of Path-line Oriented Topology in Periodic 2D Time-Dependent Vector Fields. Journal of WSCG, 2007

Title: PD
Circumference of your head (in cm):  
Firstname: Kuangyu
Lastname: Shi
Birthday: 24.05.1980
Nationality: China
Languages: English, German, Chinese
Groups: Segmentation, Reconstruction, Medical Imaging, Molecular Imaging, Machine Learning for Medical Applications
Expertise: Registration/Visualization, Segmentation, Medical Imaging, Molecular Imaging
Position: Scientific Staff
Status: Active
Emailbefore: k.shi
Emailafter: tum.de
Room: IFL
Telephone: 017624007237

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