Invited Talk by Prof. Dr. Daniel Razansky: Imaging in five dimensions - real time volumetric multispectral optoacoustic tomography

Prof. Dr. Daniel Razansky Chair for Biological Imaging Technische Universität München Date: Thursday, December 12, 2013 Time: 10:00am Location: CAMP Seminar room (MI 03.13.010)

Abstract:

Despite the ancient discovery of the basic physical phenomenon, it was not until very recently that optoacoustics was first applied to biomedical imaging, experiencing an exponential growth of technical developments and related applications in the last decade. At present, the great potential of optoacoustic imaging that was showcased in preclinical research, have encouraged translation of this technology into clinical practice with multiple applications envisioned, from cardiovascular and cancer diagnostics to ophthalmology and endoscopic imaging. One key advantage of the optoacoustic method is its intrinsic ability to deliver complete volumetric tomographic datasets from the imaged object with a single interrogating laser pulse, possibility that does not exist in other imaging modalities. This capacity comes with important advantages, such as ability to dynamically visualize biodistribution, reduce out-of-plane and motion artifacts, and accelerate clinical observations. However, multiple technical limitations related to lack of appropriate ultrasound detection technology, digital sampling and processing capacities hindered so far implementation of volumetric optoacoustic imaging system suitable for dynamic visualization of human pathology in the clinical setting. The talk concentrates on our recent efforts in translating the MSOT imaging technology into a high performance functional and molecular imaging modality routinely used in both pre-clinical research and clinical practice.