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Intra-operative Beta Probe Surface Imaging and Navigation for Optimal Tumor ResectionIn medical collaboration with:PD Dr. med. Alexander Drzezga, Nuclear Medicine Dept., Klinikum rechts der Isar, TUM, Munich, Germany Scientific Director: Nassir Navab, Sibylle Ziegler Contact Person(s): Dzhoshkun Ismail Shakir In industrial collaboration with: Dr. Farhad Daghighian, President, IntraMedical Imaging LLC, Los Angeles, CA, USA Thomas Wendler, CTO, SurgicEye GmbH, Munich, Germany |
Abstract
In minimally invasive tumor resection, the goal is to perform a minimal but complete removal of cancerous cells. In the last decades interventional beta probes supported the detection of remaining tumor cells. However, scanning the patient with an intraoperative probe and applying the treatment are not done simultaneously. The main contribution of this work is to extend the one dimensional signal of a nuclear probe to a four dimensional signal including the spatial information of the distal end of the probe. This signal can be then used to guide the surgeon in the resection of residual tissue and thus increase its spatial accuracy while allowing minimal impact on the patient.Publications
| 2012 | |
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J. Vogel, T. Reichl, J. Gardiazabal, N. Navab, T. Lasser
Optimization of Acquisition Geometry for Intra-operative Tomographic Imaging Proceedings of the 15th International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Nice, France, October 2012 (bib) |
| D. I. Shakir, A. Hartl, F. R. Schneider, J. Pulko, S. I. Ziegler, N. Navab, T. Lasser
Two new ad-hoc models of detection physics and their evaluation for navigated beta probe surface imaging Proceedings of SPIE Visualization, Image-Guided Procedures, and Modeling Conference, San Diego, CA, USA, February 2012 (bib) |
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| 2011 | |
| D. I. Shakir, T. Lasser, A. Drzezga, S. I. Ziegler, N. Navab
Evaluation of Navigated Beta-Probe Surface Imaging on a Realistic 3D Phantom Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS-MIC), Valencia, Spain, October 2011 (bib) |
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| D. I. Shakir, A. Hartl, N. Navab, S. I. Ziegler
Evaluation of an ad hoc model of detection physics for navigated beta-probe surface imaging Proceedings of SPIE Visualization, Image-Guided Procedures, and Modeling Conference, Lake Buena Vista (Orlando Area), FL, USA, February 2011 (bib) |
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| 2010 | |
| D. I. Shakir, N. Navab, S. I. Ziegler
Acquisition Model for Iterative Reconstruction of Navigated Beta-Probe Surface Images Proceedings of the IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS-MIC), Knoxville, TN, USA, November 2010 (bib) |
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| D. I. Shakir, J. Bieniarz, S. Pirsig, T. Wendler, N. Navab, S. I. Ziegler
A first study on biological feasibility of intraoperative control of tumor resection borders with navigated beta-probe surface imaging Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), Salt Lake City, UT, USA, June 2010 (bib) |
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| 2009 | |
| C. Özgür, J. Bieniarz, T. Lasser, S. I. Ziegler, N. Navab, T. Wendler
Phenomenological Models for intraoperative Positron Emission Surface Imaging using Handheld Probes Proceedings of World Congress in Medical Physics and Biomedical Engineering (WC 2009), Munich, Germany, September 2009 (bib) |
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| 2008 | |
| T. Wendler, A. Hartl, T. Lasser, J. Traub, S. I. Ziegler, N. Navab
Tracking-based statistical correction for radio-guided cancer surgery Proceedings of World Molecular Imaging Congress (WMIC 2008), Nice, France, September 2008 (bib) |
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| A. Hartl, T. Wendler, J. Traub, T. Lasser, S. I. Ziegler, N. Navab
Confident radioactivity surface reconstruction for control of resection borders Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib) |
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| N. Navab, J. Traub, A. K. Buck, S. I. Ziegler, T. Wendler
Navigated nuclear probes for intra-operative functional imaging Proceedings of 5th IEEE International Symposium on Biomedical Imaging (ISBI 2008), Paris, France, May 14 - 17 2008, pp. 1395-1398 (bib) |
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| 2007 | |
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N. Navab, J. Traub, T. Sielhorst, M. Feuerstein, C. Bichlmeier
Action- and Workflow-Driven Augmented Reality for Computer-Aided Medical Procedures IEEE Computer Graphics and Applications, vol. 27, no. 5, pp. 10-14, Sept/Oct, 2007 (bib) |
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T. Wendler, J. Traub, A. Hartl, T. Lasser, M. Burian, A. K. Buck, F. Daghighian, M. Schwaiger, S. I. Ziegler, N. Navab
Adding navigation to radio-guided surgery: new possibilities, new problems, new solutions Proceedings of Russian Bavarian Conference on Biomedical Engineering (RBC Biomed 2007), Erlangen, Germany, July 2-3, 2007, pp. 96-100 (bib) |
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T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Validation of navigated beta-probe imaging with PET/CT-generated activity surfaces. New approach in radio-guided resection for FDG-positive tumors Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2007), Washington D.C., USA, June 2007; Meeting Abstracts 48: 46P-b. (bib) |
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O. Kishenkov, T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Method for projecting functional 3D information onto anatomic surfaces: Accuracy improvement for navigated 3D beta-probes Proceedings of Bildverarbeitung fuer die Medizin (BVM 2007), Munich, Germany, March 2007, pp.66-70 (bib) |
| 2006 | |
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T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Navigated three dimensional beta probe for optimal cancer resection Proceedings of Medical Image Computing and Computer-Assisted Intervention (MICCAI 2006), Copenhagen, Denmark, October 1-6 2006, LNCS 4190 (1), pp. 565-569 (bib) |
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Location
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Klinikum rechts der Isar der Technischen Universitüt München Ismaninger Str. 22 81675 München IFL Lab - Room: 01.3a-c Tel.: +49 89 4140-6457 Fax: +49 89 4140-6458 |
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internal project page
Please contact Dzhoshkun Ismail Shakir for available student projects within this research project.
