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Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

S. Atasoy, D. Mateus, A. Meining, G. Z. Yang, N. Navab
Targeted Optical Biopsies for Surveillance Endoscopies
Medical Image Computing and Computer Assisted Intervention (MICCAI), Toronto, Canada, September 20-24 2011. (bib)

Recent introduction of probe-based confocal laser endomicroscopy (pCLE) allowed for the acquisition of in-vivo optical biopsies during the endoscopic examination without removing any tissue sample. The non-invasive nature of the optical biopsies makes the re-targeting of previous biopsy sites in surveillance examinations dfficult due to the absence of scar or surface landmarks. In this work, we introduce a new method for recognition of optical biopsy scenes of the diagnosis endoscopy during serial surveillance examinations. To this end, together with our clinical partners, we propose a new work ow involving two-run surveillance endoscopies to reduce the ill-posedness of the task. In the first run, the endoscope is guided from the mouth to the z-line (junction from the oesophagus to the stomach). Our method relies on clustering the frames of the diagnosis and the firrst run surveillance (S1) endoscopy into several scenes and establishing cluster correspondences accross these videos. During the second run surveillance (S2), the scene recognition is performed in real-time and in-vivo based on the cluster correspondences. Detailed experiment results demonstrate the feasibility of the proposed approach with 89.75% recall and 80.91% precision on 3 patient datasets.
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