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Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

G. Fallo, M. Cencini, PA. Gómez, D. Bacciu, A. Cisternino, M. Tosetti, G. Buonincontri
Schedule design for parameter quantification in the transient state using Bayesian optimization
PSMR 2018: 7th Conference on PET/MR and SPECT/MR (bib)

Magnetic resonance fingerprinting (MRF) is a new quantitative imaging paradigm, which simultaneously acquires multiple tissue parameters in an efficient experiment. MRF can map several parameters simultaneously including T1, T2, and spin density. However, it is important to underline that specific sequences may be better suited for certain parameter ranges or sampling patterns. This work aims to introduce a framework for pulse sequence optimization, individually optimizing for T1 or T2 relaxation times. We demonstrate a new method, including undersampled acquisitions, by simulating the MRI signal encoding, gridding, and pattern recognition directly in the optimization. The design framework could obtain efficient schedules for T1 and T2 acquisition.
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