S. Kraft, A. Karamalis, D. Sheet, E. Drecoll, E. Rummeny, N. Navab, P. B. Noël, A. Katouzian Introducing nuclei scatterer patterns into histology-based intravascular ultrasound simulation framework To appear in: SPIE Medical Imaging 2013 (bib)
	We introduce a framework to simulate intravascular ultrasound (IVUS) from histological sections. These sections were previously acquired along with real IVUS radiofrequency signals using single-element 40MHz transducer. After labeling and registering the section to the corresponding IVUS image, a virtual phantom was created, incorporating nuclei scatterer patterns. A finite differences simulation of the acoustic signal was performed, resulting in backscattered radiofrequency signals. These were used to process a B-mode image, which in turn was compared to the real IVUS image of the same section. A high image quality with a very promising correlation to the original IVUS images was achieved.
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