A. Kamen, W. Wein, P. Khurd, M. Diallo, R. Nanke, J. Fehre, B. Kiefer, M. Requardt, C. Weiss System and method for image guided prostate cancer needle biopsy US Grant US9521994B2 (bib)
	In a method for image guided prostate cancer needle biopsy, a first registration is performed to match a first image of a prostate to a second image of the prostate. Third images of the prostate are acquired and compounded into a three-dimensional (3D) image. The prostate in the compounded 3D image is segmented to show its border. A second registration and then a third registration different from the second registration is performed on distance maps generated from the prostate borders of the first image and the compounded 3D image, wherein the first and second registrations are based on a biomechanical property of the prostate. A region of interest in the first image is mapped to the compounded 3D image or a fourth image of the prostate acquired with the second modality.
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