|M. Wieczorek, F. Schaff, C. Jud, D. Pfeiffer, F. Pfeiffer, T. Lasser
Brain Connectivity Exposed by Anisotropic X-ray Dark-field Tomography
Sci. Rep. 8:14345, 2018 (bib)
|To understand the interaction of different parts of the human brain it is essential to know how they are connected. Such connections are predominantly related to the brainâ€™s white matter, which forms the neuronal pathways, the axons. These axons, also referred to as nerve fibers, have a size on the micrometer scale and are therefore too small to be imaged by standard X-ray systems. In this paper, we use a grating interferometer and a method based on Anisotropic X-ray Dark-field Tomography (AXDT) with the goal to generate a three-dimensional tomographic reconstruction of these functional structures. A first preclinical survey shows that we successfully reconstruct the orientations of the brain fibers connectivity with our approach.
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