PhD defense by Kanishka Sharma

Speaker: Kanishka Sharma Date: Wednesday, November 22, 2017 Time: 10:00 Location: FMI-Building, Room 01.09.014

Machine Learning Methods for Segmentation in Autosomal Dominant Polycystic Kidney Disease

Abstract:

In Autosomal Dominant Polycystic Kidney Disease (ADPKD), automated segmentation of kidneys for total kidney volume (TKV) measurement is very challenging due to severe, disease-related alterations in kidney morphology. This PhD thesis analyzes the applicability and performance of machine learning techniques (Random Forests and Deep Learning) for kidney segmentation in ADPKD. The developed segmentation method based on Deep Learning allows fast and reproducible TKV measurements, demonstrating that machine learning can be successfully used for complex medical image segmentation tasks.