ProjectCoronaryIVUSCT

Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

Assessment of Fluid Tissue Interaction Using Multi-Modal Image Fusion for Characterization and Progression of Coronary Atherosclerosis

Assessment of Fluid Tissue Interaction Using Multi-Modal Image Fusion for Characterization and Progression of Coronary Atherosclerosis

In medical collaboration with:
Department of Cardiology, Medizinische Poliklinik der Universität München (Germany)
Department of Cardiology, Faculty of Medicine, Yeditepe Üniversitesi (Turkey)

Scientific Director: Prof. Dr. Nassir Navab and Assoc. Prof. Dr. Gözde Ünal, Sabanci Üniversitesi (Turkey)

Contact Person(s): Olivier Pauly and Stefanie Demirci

Keywords: Registration / Visualization, Segmentation, Medical Imaging

Abstract

Coronary artery diseases such as atherosclerosis are the leading cause of death in the industrialized world. In this project, we develop computational tools for segmentation and registration problems on intravascular images including IVUS (Intravascular Ultrasound) and OCT (Optical Coherence Tomography). One sample component of this project is Automatic Stent Implant Follow-up from Intravascular OCT Pullbacks. The stents are automatically detected and their distribution is analyzed for monitoring of the stents: their malpositioning and/or tissue growth over stent struts.

Pictures

Figure 1: CFD of main coronary artery

Publications

Clinical Relevance

Coronary Artery Disease (CAD) still remains the leading cause of morbidity and mortality among western countries. The appearance of CAD can range from stable angina pectoris to acute coronary syndromes (ACS), which are associated with increased mortality. Acute coronary syndromes are usually caused by acute plaque rupture, which leads to local thrombosis and occlusion of the respective coronary vessel. The localization of atherosclerotic lesions is not randomly distributed but show a characteristic pattern with preferred location at branches or bends. This results in locally different shear stress levels and flow-tissue interaction which can promote atherosclerosis.

Team

Contact Person(s)

Olivier Pauly
Dipl.-Ing. Univ. Olivier Pauly
Stefanie Demirci
Dr. Stefanie Demirci

Working Group

Gozde Isguder
Gozde Isguder
Martin Groher
Dr. Martin Groher

Alumni

Arash Taki
Dr. Arash Taki

Location



Technische Universität München
Institut für Informatik / I16
Boltzmannstr. 3
85748 Garching bei München

Tel.: +49 89 289-17058
Fax: +49 89 289-17059
Visit our lab at Garching.



Ludwig-Maximilians-Universität München
Chirurgische Klinik und Poliklinik - Innenstadt, AG CAS
Nussbaumstr. 20
80336 München

Room: C2.06
Tel.: +49 89 5160-3615
Tel.: +49 89 5160-3635
Fax: +49 89 5160-3630
Visit our lab at Klinikum Innenstadt.



internal project page

Please contact Olivier Pauly and Stefanie Demirci for available student projects within this research project.

Edit | Attach | Refresh | Diffs | More | Revision r1.1 - 12 Jan 2011 - 09:55 - StefanieDemirci

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