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Dr. Oliver Zettinig Mail: ImFusion GmbH Agnes-Pockels-Bogen 1 80992 München, Germany +49 89 452 46 78 96 Personal website: zettinig.eu |
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Advanced Ultrasound Imaging Techniques for Computer Assisted Interventions
Abstract: This thesis addresses several challenges associated with medical ultrasound in interventional scenarios. The main contributions include novel image registration algorithms, innovative control laws for robotic navigation using visual servoing, as well as an original method to reconstruct 3D velocity fields over time from Doppler information. The clinical suitability of the developed methods is thoroughly validated on human data within prostate biopsy guidance, robotic needle navigation, and blood vessel screening applications. Download: http://mediatum.ub.tum.de?id=1345760 |
Prostate Fusion BiopsyTransrectal ultrasound (TRUS) guided biopsy remains the gold standard for diagnosis. However, it suffers from low sensitivity, leading to an elevated rate of false negative results. On the other hand, the recent advent of PET imaging using a novel dedicated radiotracer, Ga-labelled PSMA (Prostate Specific Membrane Antigen), combined with MR provides improved preinterventional identification of suspicious areas. Thus, MRI/TRUS fusion image-guided biopsy has evolved to be the method of choice to circumvent the limitations of TRUS-only biopsy. We propose a multimodal fusion image-guided biopsy framework that combines PET-MRI images with TRUS. Based on open-source software libraries, it is low cost, simple to use and has minimal overhead in clinical workflow. It is ideal as a research platform for the implementation and rapid bench to bedside translation of new image registration and visualization approaches. |
Advanced Robotics for Multi-Modal Interventional Imaging (RoBildOR)This project aims at developing advanced methods for robotic image acquisitions, enabling more flexible, patient- and process-specific functional and anatomical imaging with the operating theater. Using robotic manipulations, co-registered and dynamic imaging can be provided to the surgeon, allowing for optimal implementation of preoperative planning. In particular, this projects is the first one developing concepts for intraoperative SPECT-CT, and introduces intraoperative robotic Ultrasound imaging based on CT trajectory planning, enabling registration with angiographic data. With distinguished partners from Bavarian industry, this project has a fundamental contribution in developing safe, reliable, flexible, and multi-modal imaging technologies for the operating room of the future. |
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MICCAI Young Scientist Award 2013 |
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3rd Best Student Paper Award 2017 |
2020 | |||||||||||||||||||||||||||||||||||||||||||||
W. Wein, M. Lupetti, O. Zettinig, S. Jagoda, M. Salehi, V. Markova, D. Zonoobi, R. Prevost
Three-dimensional thyroid assessment from untracked 2D ultrasound clips Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2020, October 2020 (bib) |
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2018 | |||||||||||||||||||||||||||||||||||||||||||||
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O. Zettinig, M. Salehi, R. Prevost, W. Wein
Recent Advances in Point-of-Care Ultrasound using the ImFusion Suite for Real-Time Image Analysis Proceedings of MICCAI Workshop Point-of-Care Ultrasound: Algorithms, Hardware, and Applications (POCUS), Granada, Spain, September 2018 (bib) |
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R. Prevost, M. Salehi, S. Jagoda, S. Kumar, J. Sprung, A. Ladikos, R. Bauer, O. Zettinig, W. Wein
3D Freehand Ultrasound without External Tracking using Deep Learning Medical Image Analysis, Volume 48, August 2018, Pages 187-202 (MICCAI Special Issue) (bib) |
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J. Esteban, W. Simson, S. Requena, A. Rienmüller, S. Virga, O. Zettinig, B. Frisch, S. Drazen, Y.-M. Ryang , N. Navab, C. Hennersperger
Robotic Ultrasound-Guided Facet Joint Insertion International Journal of Computer Assisted Radiology and Surgery / 9th International Conference on Information Processing in Computer-Assisted Interventions (IPCAI), Berlin, Germany, June 2018. (bib) |
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2017 | |||||||||||||||||||||||||||||||||||||||||||||
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R. Kojcev, A. Khakzar, B. Fuerst, O. Zettinig, C. Fakhry, R. DeJong, J. Richmon, R. Taylor, E. Sinibaldi, N. Navab
On the Reproducibility of Expert-Operated and Robotic Ultrasound Acquisitions International Journal of Computer Assisted Radiology and Surgery / International Conference on Information Processing in Computer-Assisted Interventions (IPCAI), Barcelona, June 2017. ![]() O. Zettinig, J. Rackerseder, B. Lentes, T. Maurer, K. Westenfelder, M. Eiber, B. Frisch, N. Navab
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Preconditioned Intensity-Based Prostate Registration using Statistical Deformation Models IEEE International Symposium on Biomedical Imaging (ISBI), Melbourne, April 2017. (bib) ![]() O. Zettinig, B. Frisch, S. Virga, M. Esposito, A. Rienmüller, B. Meyer, C. Hennersperger, Y.-M. Ryang , N. Navab
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3D Ultrasound Registration-based Visual Servoing for Neurosurgical Navigation International Journal of Computer Assisted Radiology and Surgery, Volume 12, Issue 9, pp 1607–1619, 2017. The original publication is available online at link.springer.com (bib) 2016 | ![]() B. Frisch, O. Zettinig, B. Fuerst, S. Virga, C. Hennersperger, N. Navab
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Collaborative Robotic Ultrasound: Towards Clinical Application Radiological Society of North America Annual Meeting, Chicago, USA, 2016 (bib) ![]() C. Hennersperger, B. Fuerst, S. Virga, O. Zettinig, B. Frisch, T. Neff, N. Navab
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Towards MRI-Based Autonomous Robotic US Acquisitions: A First Feasibility Study IEEE Transactions on Medical Imaging, vol. 36, iss. 2, 2017 The original publication (open access) is available online at ieeexplore.ieee.org (bib) ![]() S. Virga, O. Zettinig, M. Esposito, K. Pfister, B. Frisch, T. Neff, N. Navab, C. Hennersperger
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Automatic Force-Compliant Robotic Ultrasound Screening of Abdominal Aortic Aneurysms IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), Daejeon, South Korea, October 2016. The original publication is available online at ieeexplore.ieee.org (bib) ![]() R. Kojcev, B. Fuerst, O. Zettinig, J. Fotouhi, S.C. Lee, B. Frisch, R. Taylor, E. Sinibaldi, N. Navab
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Dual-Robot Ultrasound-Guided Needle Placement: Closing the Planning-Imaging-Action Loop International Journal of Computer Assisted Radiology and Surgery / International Conference on Information Processing in Computer-Assisted Interventions (IPCAI), Heidelberg, June 2016. The original publication is available online at link.springer.com (bib) ![]() O. Zettinig, B. Fuerst, R. Kojcev, M. Esposito, M. Salehi, W. Wein, J. Rackerseder, B. Frisch, N. Navab
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Toward Real-time 3D Ultrasound Registration-based Visual Servoing for Interventional Navigation IEEE International Conference on Robotics and Automation (ICRA), Stockholm, May 2016. The original publication is available online at ieeexplore.ieee.org (bib) 2015 | ![]() O. Zettinig, A. Shah, C. Hennersperger, M. Eiber, C. Kroll, H. Kübler, T. Maurer, F. Milletari, J. Rackerseder, C. Schulte-zu-Berge, E. Storz, B. Frisch, N. Navab
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Multimodal Image-Guided Prostate Fusion Biopsy based on Automatic Deformable Registration International Journal of Computer Assisted Radiology and Surgery / 6th International Conference on Information Processing in Computer-Assisted Interventions (IPCAI), Barcelona, June 2015. The original publication is available online at link.springer.com (bib) ![]() A. Shah, O. Zettinig, E. Storz, T. Maurer, M. Eiber, N. Navab, B. Frisch
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Challenges in Multimodal Image-guided Targeted Prostate Biopsy Hamlyn Symposium on Medical Robotics, London, UK, June 2015 (bib) ![]() B. Frisch, E. Storz, O. Zettinig, A. Shah, H. Kübler, N. Navab, HP Wester, M. Schwaiger, M. Eiber, T. Maurer
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PET/MRI/TRUS image fusion guided prostate biopsy: development of a research platform and initial clinical results Society of Nucler Medicine and Medical Imaging Annual Meeting, Baltimore, USA, 2015 (bib) ![]() E. Storz, A. Shah, O. Zettinig, M. Eiber, H.-J. Wester, H. Kübler, J. Gschwend, M. Schwaiger, B. Frisch, T. Maurer
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PSMA-PET/MRI-guided fusion biopsy for the detection of prostate cancer Annual Congress of European Association of Urology (EAU), Madrid, March 2015 (bib) 2014 | ![]() O. Zettinig, C. Hennersperger, C. Schulte-zu-Berge, M. Baust, N. Navab
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3D Velocity Field and Flow Profile Reconstruction from Arbitrarily Sampled Doppler Ultrasound Data Proceedings of the 17th International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Boston, USA, September 2014. The original publication is available online at link.springer.com (bib) ![]() A. Shah, O. Zettinig, T. Maurer, C. Precup, C. Schulte-zu-Berge, J. Weiss, B. Frisch, N. Navab
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An Open Source Multimodal Image-guided Prostate Biopsy Framework 3rd Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging (CLIP), 17th MICCAI, MIT, Boston, USA, September 2014. The original publication is available online at link.springer.com (bib) ![]() O. Zettinig, T. Mansi, D. Neumann, B. Georgescu, S. Rapaka, P. Seegerer, E. Kayvanpour, F. Sedaghat-Hamedani, A. Amr, J. Haas, H. Steen, H. Katus, B. Meder, N. Navab, A. Kamen, D. Comaniciu
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Data-Driven Estimation of Cardiac Electrical Diffusivity from 12-Lead ECG Signals Medical Image Analysis, vol. 18, iss. 8, pp. 1361-1376, 2014. The original publication is available online at medicalimageanalysisjournal.com (bib) 2013 | ![]() T. Mansi, R. Beinart, O. Zettinig, S. Rapaka, B. Georgescu, A. Kamen, Y. Dori, M.M. Zviman, D.A. Herzka, H.R. Halperin, D. Comaniciu
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A Framework for the Pre-clinical Validation of LBM-EP for the Planning and Guidance of Ventricular Tachycardia Ablation Proceedings of MICCAI Workshop on Statistical Atlases and Computational Models of the Heart (STACOM), Nagoya, Japan, September 2013. The original publication is available online at link.springer.com (bib) ![]() O. Zettinig, T. Mansi, B. Georgescu, E. Kayvanpour, F. Sedaghat-Hamedani, A. Amr, J. Haas, H. Steen, B. Meder, H. Katus, N. Navab, A. Kamen, D. Comaniciu
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Fast Data-Driven Calibration of a Cardiac Electrophysiology Model from Images and ECG Proceedings of the 16th International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Nagoya, Japan, September 2013. The original publication is available online at link.springer.com (bib) ![]() B. Georgescu, S. Rapaka, T. Mansi, O. Zettinig, A. Kamen, D. Comaniciu
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Towards Real-Time Cardiac Electrophysiology Computations Using GP-GPU Lattice-Boltzmann Method Proceedings of MICCAI Workshop on High Performance Computing for Biomedical Image Analysis (HPC-MICCAI), Nagoya, Japan, September 2013 (bib) ![]() O. Zettinig, T. Mansi, B. Georgescu, S. Rapaka, A. Kamen, J. Haas, K.S. Frese, F. Sedaghat-Hamedani, E. Kayvanpour, A. Amr, S. Hardt, D. Mereles, H. Steen, A. Keller, H. Katus, B. Meder, N. Navab, D. Comaniciu
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From Medical Images to Fast Computational Models of Heart Electromechanics: An Integrated Framework towards Clinical Use Proceedings of the 7th International Conference on Functional Imaging and Modeling of the Heart (FIMH), London, UK, June 2013. The original publication is available online at link.springer.com (bib) |
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Title: | Dr. |
Circumference of your head (in cm): | |
Firstname: | Oliver |
Middlename: | |
Lastname: | Zettinig |
Picture: | ![]() |
Birthday: | 17.07.1988 |
Nationality: | Austria |
Languages: | English, German |
Groups: | Medical Imaging, IFL, Ultrasound |
Expertise: | Medical Imaging |
Position: | Scientific Staff |
Status: | Alumni |
Emailbefore: | oliver.zettinig |
Emailafter: | tum.de |
Room: | |
Telephone: | |
Alumniactivity: | Senior Research Scientist at ImFusion GmbH |
Defensedate: | 6 October 2017 |
Thesistitle: | Advanced Ultrasound Imaging Techniques for Computer Assisted Interventions |
Alumnihomepage: | |
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