Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

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Automatic Progression Tracking of Skin Lesions

Automatic Progression Tracking of Skin Lesions

In medical collaboration with:
Prof. Dr. Dr. Jürgen Becker, Chefarzt, Dermatology, Universitätsklinikum Graz, Graz,
Austria Prof. Dr. Johannes Ring, Director, Dermatology, Klinikum Rechts der Isar, TUM, Munich, Germany;
Prof. Dr. Rüdiger Hein, Clinical Research Director, Dermatology, Klinikum Rechts der Isar, TUM, Munich, Germany

Scientific Director: Nassir Navab

Contact Person(s): Alexandru Duliu, Tobias Lasser

Keywords: Medical Imaging, Medical Augmented Reality, 3D Information Presentation


The aim of this project is to investigate, design, and implement a novel prototype device capable of acquiring the skin surface in multiple spectral bands and generating a 3D reconstruction of it. The reconstruction will allow the system to compare quantitatively the results with any previous one, and show the physician the evolution of a skin lesion. Moreover, the software will also search for melanocytic skin lesions suspicious for melanoma using established medical criteria, and assist the physician to check these suspicious lesions in more detail through the multispectral information. This will provide the physician with a tool that documents the evolution of skin lesions allowing to follow these objectively over time irrespective of common problems like tanning, body weight changes, deformation, etc. The final goal is to improve skin cancer detection stages when therapeutic intervention results in survival rate close to 100%, as well as to provide a tool for the quantitative evaluation of skin cancer types such as cutaneous lymphoma that have to be monitored over time. This approach should increase not only the detection sensitivity but also specificity; an important notion particularly for patients with several atypical naevi for which the false negative rate is over 80%. The scanner will then also be a tool to reduce the number of unnecessary biopsies.


A. Duliu, T. Lasser, T. Wendler, A. Safi, S. I. Ziegler, N. Navab
Navigated Tracking of Skin Lesion Progression with Optical Spectroscopy
Proceedings of SPIE Vol. 7624, 76243P (2010) (bib)
T. Lasser, A. Duliu, T. Wendler, J. Becker, S. I. Ziegler, N. Navab
Computer-assisted spectral quantification of disease progression in CTCL
Proceedings of World Molecular Imaging Congress (WMIC 2008), Nice, France, September 2008 (bib)
T. Lasser, A. Duliu, T. Wendler, S. I. Ziegler, N. Navab
Navigated tracking of skin lesion progression with optical spectroscopy
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib)


Contact Person(s)

Alexandru Duliu
Dipl.-Inf. Univ. Alexandru Duliu
Tobias Lasser
PD Tobias Lasser

Working Group

Nassir Navab
Prof. Dr. Nassir Navab
Sibylle Ziegler
Prof. Dr. Sibylle Ziegler


Asad Safi
Dr. Asad Safi
Jose Gardiazabal
Dipl.-Ing. Univ. Jose Gardiazabal
Juergen Becker
Prof. Dr. Juergen Becker
Thomas Wendler
Dr. Thomas Wendler


Klinikum rechts der Isar
der Technischen Universitüt München
Ismaninger Str. 22
81675 München

IFL Lab - Room: 01.3a-c
Tel.: +49 89 4140-6457
Fax: +49 89 4140-6458
Visit our lab at Klinikum rechts der Isar.

internal project page

Please contact Alexandru Duliu, Tobias Lasser for available student projects within this research project.

Edit | Attach | Refresh | Diffs | More | Revision r1.1 - 03 Apr 2008 - 10:22 - ThomasWendler

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