Automatic Progression Tracking of Skin Lesions In medical collaboration with: Prof. Dr. Dr. Jürgen Becker, Chefarzt, Dermatology, Universitätsklinikum Graz, Graz, Austria Prof. Dr. Johannes Ring, Director, Dermatology, Klinikum Rechts der Isar, TUM, Munich, Germany; Prof. Dr. Rüdiger Hein, Clinical Research Director, Dermatology, Klinikum Rechts der Isar, TUM, Munich, Germany Scientific Director: Nassir Navab Contact Person(s): Alexandru Duliu, Tobias Lasser

Keywords: Medical Imaging, Medical Augmented Reality, 3D Information Presentation

Abstract

The aim of this project is to investigate, design, and implement a novel prototype device capable of acquiring the skin surface in multiple spectral bands and generating a 3D reconstruction of it. The reconstruction will allow the system to compare quantitatively the results with any previous one, and show the physician the evolution of a skin lesion. Moreover, the software will also search for melanocytic skin lesions suspicious for melanoma using established medical criteria, and assist the physician to check these suspicious lesions in more detail through the multispectral information. This will provide the physician with a tool that documents the evolution of skin lesions allowing to follow these objectively over time irrespective of common problems like tanning, body weight changes, deformation, etc. The final goal is to improve skin cancer detection stages when therapeutic intervention results in survival rate close to 100%, as well as to provide a tool for the quantitative evaluation of skin cancer types such as cutaneous lymphoma that have to be monitored over time. This approach should increase not only the detection sensitivity but also specificity; an important notion particularly for patients with several atypical naevi for which the false negative rate is over 80%. The scanner will then also be a tool to reduce the number of unnecessary biopsies.

Publications

2010
	A. Duliu, T. Lasser, T. Wendler, A. Safi, S. I. Ziegler, N. Navab Navigated Tracking of Skin Lesion Progression with Optical Spectroscopy Proceedings of SPIE Vol. 7624, 76243P (2010) (bib)
2008
	T. Lasser, A. Duliu, T. Wendler, J. Becker, S. I. Ziegler, N. Navab Computer-assisted spectral quantification of disease progression in CTCL Proceedings of World Molecular Imaging Congress (WMIC 2008), Nice, France, September 2008 (bib)
	T. Lasser, A. Duliu, T. Wendler, S. I. Ziegler, N. Navab Navigated tracking of skin lesion progression with optical spectroscopy Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib)

Team

Contact Person(s)

Dipl.-Inf. Univ. Alexandru Duliu

PD Tobias Lasser

Working Group

Prof. Dr. Nassir Navab

Prof. Dr. Sibylle Ziegler

Alumni

Dr. Asad Safi

Dipl.-Ing. Univ. Jose Gardiazabal

Prof. Dr. Juergen Becker

Dr. Thomas Wendler

Location

Klinikum rechts der Isar der Technischen Universitüt München Ismaninger Str. 22 81675 München IFL Lab - Room: 01.3a-c Tel.: +49 89 4140-6457 Fax: +49 89 4140-6458

Visit our lab at Klinikum rechts der Isar.



internal project page

Please contact Alexandru Duliu, Tobias Lasser for available student projects within this research project.