PublicationDetail

Chair for Computer Aided Medical Procedures & Augmented Reality
Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality

THIS WEBPAGE IS DEPRECATED - please visit our new website

W. Wein, B. Röper, N. Navab
Integrating diagnostic B-mode ultrasonography into CT-based radiation treatment planning
IEEE Transactions on Medical Imaging, 26 (June 2007), pp. 866–879 (bib)

This paper presents methods and a clinical procedure for integrating B-mode ultrasound images tagged with position information with a planning CT scan for radiotherapy. A workflow is described that allows the integration of these modalities into the clinic. A surface mapping approach provides a pre-registration of the ultrasound image borders onto the patient's skin. Successively, a set of individual ultrasound images from a freehand sweep is chosen by the physician. These images are automatically registered with the planning CT scan using novel intensity-based methods. We put a particular focus on deriving an appropriate similarity measure based on the physical properties and artifacts of ultrasound. A combination of a weighted Mutual Information term, edge correlation, clamping to the skin surface and occlusion detection is able to assess the alignment of structures in ultrasound images and information reconstructed from the CT data. We demonstrate the practicality of our methods on five patients with head and neck tumors and cervical lymph node metastases, and provide a detailed report on the conducted experiments, including the setup, calibration, acquisition, and verification of our algorithms. The mean Target Registration Error (TRE) on 9 data sets is 3.9mm. Thus, the additional information about intranodal architecture and fulfillment of malignancy criteria derived from a high-resolution ultrasonography of lymph nodes can be localized and visualized in the CT scan coordinate space and is made available for further radiation treatment planning.
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each authors copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.



Edit | Attach | Refresh | Diffs | More | Revision r1.13 - 30 Jan 2019 - 15:16 - LeslieCasas

Lehrstuhl für Computer Aided Medical Procedures & Augmented Reality    rss.gif