Julia Rackerseder

Julia Rackerseder Mail: julia.rackerseder@tum.de Address Garching: Chair for Computer Aided Medical Procedures & Augmented Reality Fakultät für Informatik Technische Universität München Boltzmannstr. 3 85748 Garching b. München Room: MI 03.13.043 Phone: +49 89 289 19403 Address Klinikum rechts der Isar: Klinikum Rechts der Isar Interdisziplinäres Forschungslabor Ismaninger Str. 22 81675 München Room: Building 501 - 01.3a-c Phone: +49 89 4140 6457

Teaching

• Praktikum MedInnovate: From unmet clinical needs to solution concepts (2019WiSe)
• Hauptseminar Lost in Translation: The Challenges of Research Transfer into Clinical Practice (2019SoSe)
• Praktikum MedInnovate: From unmet clinical needs to solution concepts (2018WiSe)
• Hauptseminar Lost in Translation: The Challenges of Research Transfer into Clinical Practice (2018SoSe)
• Praktikum MedInnovate: From unmet clinical needs to solution concepts (2018SoSe)
• Praktikum BioInnovation: From unmet clinical needs to solution concepts (2017WiSe)
• Praktikum BioInnovation: From unmet clinical needs to solution concepts (2017SoSe)
• Hauptseminar Brain Tumor Treatment - Ethical Standards, Medical challenges, Technological Future (2017SoSe)
• Praktikum BioInnovation : from unmet clinical needs to solution concepts (2016WiSe)
• Hauptseminar Image-based tool tracking for computer aided biopsy procedures (2016WiSe)
• Praktikum BioInnovation: from unmet clinical needs to solution concepts (2016SoSe)
• Praktikum BioInnovation: from unmet clinical needs to solution concepts (2015WiSe)
• Hauptseminar Crowdsourcing and Gamification with Applications to Computer Vision (IN0014, IN2107) (2015WiSe)

Research interests and topics

• Brains, brains, brains!
• Computer assisted neurosurgery
• Functional and anatomical atlas generation
• Multi-modal image registration
• Rapid prototyping
• Tissue conservation techniques
• Tissue models for functional, anatomical, multi-modal imaging

Active Research Projects

Prostate Fusion Biopsy Transrectal ultrasound (TRUS) guided biopsy remains the gold standard for diagnosis. However, it suffers from low sensitivity, leading to an elevated rate of false negative results. On the other hand, the recent advent of PET imaging using a novel dedicated radiotracer, Ga-labelled PSMA (Prostate Specific Membrane Antigen), combined with MR provides improved preinterventional identification of suspicious areas. Thus, MRI/TRUS fusion image-guided biopsy has evolved to be the method of choice to circumvent the limitations of TRUS-only biopsy. We propose a multimodal fusion image-guided biopsy framework that combines PET-MRI images with TRUS. Based on open-source software libraries, it is low cost, simple to use and has minimal overhead in clinical workflow. It is ideal as a research platform for the implementation and rapid bench to bedside translation of new image registration and visualization approaches.

EDEN2020: Enhanced Delivery Ecosystem for Neurosurgery EDEN2020 (Enhanced Delivery Ecosystem for Neurosurgery) aims to develop the gold standard for one-stop diagnosis and treatment of brain disease by delivering an integrated technology platform for minimally invasive neurosurgery. A team of first-class industrial partners (Renishaw plc. and XoGraph ltd.), leading clinical oncological neurosurgery team (Università di Milano, San Raffaele and Politecnico di Milano) lead by Prof. Lorenzo Bello and the involvement of leading experts in shape sensing (Universitair Medisch Centrum Groningen) under supervision of Prof. Dr. Sarthak Misra The project is coordinated by Dr. Rodriguez y Baena, Imperial College London. His team provides the core technology for the envisioned system, the bendable robotic needle. During the course of EDEN2020 this interdisciplinary team will work on the integration of 5 key concepts, namely (1) pre-operative MRI and diffusion-MRI imaging, (2) intra-operative ultrasounds, (3) robotic assisted catheter steering, (4) brain diffusion modelling, and (5) a robotics assisted neurosurgical robotic product (the Neuromate), into a pre-commercial prototype which meets the pressing demand for better and less invasive neurosurgery. Our chair will be focusing on the imaging components (i.e. (1) and (2)), targeting the realtime compensation of tissue movement and accurate localization of the flexible catheters at hand. We will further extend the findings of FP7 ACTIVE, in which we successfully combined pre-operative MRI with intra-operative US through deformable 3D-2D registration, making us most qualified for this role.

MedInnovate: From unmet clinical needs to solution concepts Learn how to successfully identify unmet clinical needs within the clinical routine and work towards possible and realistic solutions to solve those needs. Students will get to know tools helping them to be successful innovators in medical technology. This will include all steps from needs finding and selection to defining appropriate solution concepts, including the development of first prototypes. Get introduced to necessary steps for successful idea and concept creation and realize your project in an interdisciplinary teams comprising of physicists, informations scientists and business majors. During the project phase, you are supported by coaches from both industry and medicine, in order to allow for direct and continuous exchange.

List of Publications

2019
	B. Demiray, J. Rackerseder, S. Bozhinoski, N. Navab Weakly-Supervised White and Grey Matter Segmentation in 3D Brain Ultrasound arxiv (bib)
	J. Rackerseder, M. Baust, R. Göbl, N. Navab, C. Hennersperger Landmark-Free Initialization of Multi-Modal Image Registration Bildverarbeitung fuer die Medizin (BVM), Luebeck, March 17-19, 2019. (bib)
2018
	K. Westenfelder, B. Lentes, J. Rackerseder, N. Navab, J. Gschwend, M. Eiber, C. R. Maurer, Jr. Gallium-68 HBED-CC-PSMA Positron Emission Tomography/Magnetic Resonance Imaging for Prostate Fusion Biopsy Clinical genitourinary cancer, August 2018, Volume 16, Issue 4, Pages 245-247 (bib)
	J. Rackerseder, M. Baust, R. Göbl, N. Navab, C. Hennersperger Initialize globally before acting locally: Enabling Landmark-free 3D US to MRI Registration 21st International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Granada, Spain, September 2018 (bib)
	B. Busam, P. Ruhkamp, S. Virga, B. Lentes, J. Rackerseder, N. Navab, C. Hennersperger Markerless Inside-Out Tracking for 3D Ultrasound Compounding International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Point-of-Care Ultrasound, Granada, Spain, September 2018 [oral]. (bib)
2017
	O. Zettinig, J. Rackerseder, B. Lentes, T. Maurer, K. Westenfelder, M. Eiber, B. Frisch, N. Navab Preconditioned Intensity-Based Prostate Registration using Statistical Deformation Models IEEE International Symposium on Biomedical Imaging (ISBI), Melbourne, April 2017. (bib)
	J. Rackerseder, A. Luque, C. Düwel, N. Navab, B. Frisch Fully automated multi-modal anatomic atlas generation using 3D-Slicer Workshops Bildverarbeitung fuer die Medizin (BVM), Heidelberg, March 12-14, 2017. (bib)
	R. Göbl, S. Virga, J. Rackerseder, B. Frisch, N. Navab, C. Hennersperger Acoustic window planning for ultrasound acquisition International Journal of Computer Assisted Radiology and Surgery / 8th International Conference on Information Processing in Computer-Assisted Interventions (IPCAI), Barcelona, Spain, June 2017. The original publication is available online at link.springer.com (bib)
2016
	M. Esposito, B. Busam, C. Hennersperger, J. Rackerseder, N. Navab, B. Frisch Multimodal US-Gamma Imaging using Collaborative Robotics for Cancer Staging Biopsies International Journal of Computer Assisted Radiology and Surgery (bib)
	O. Zettinig, B. Fuerst, R. Kojcev, M. Esposito, M. Salehi, W. Wein, J. Rackerseder, B. Frisch, N. Navab Toward Real-time 3D Ultrasound Registration-based Visual Servoing for Interventional Navigation IEEE International Conference on Robotics and Automation (ICRA), Stockholm, May 2016. The original publication is available online at ieeexplore.ieee.org (bib)
2015
	M. Esposito, B. Busam, C. Hennersperger, J. Rackerseder, A. Lu, N. Navab, B. Frisch Cooperative Robotic Gamma Imaging: Enhancing US-guided Needle Biopsy Proceedings of the 18th International Conference on Medical Image Computing and Computer Assisted Interventions (MICCAI), Munich, Germany, October 2015 [oral]. (bib)
	O. Zettinig, A. Shah, C. Hennersperger, M. Eiber, C. Kroll, H. Kübler, T. Maurer, F. Milletari, J. Rackerseder, C. Schulte-zu-Berge, E. Storz, B. Frisch, N. Navab Multimodal Image-Guided Prostate Fusion Biopsy based on Automatic Deformable Registration International Journal of Computer Assisted Radiology and Surgery / 6th International Conference on Information Processing in Computer-Assisted Interventions (IPCAI), Barcelona, June 2015. The original publication is available online at link.springer.com (bib)