Hiwi position for Medicine student: Validation of Navigated Beta Probe Application in Cancer Surgery

Eventually, this project could be transformed into an Medicine Doctor thesis supervised by Prof. Navab and a Prof. of Surgery to be defined.

Advisor: Nassir Navab
Supervision by: Joerg Traub and Thomas Wendler

Abstract

In minimally invasive tumor resection, the desirable goal is to perform a minimal but complete removal of cancerous cells. In the last decades interventional nuclear medicine probes supported the detection of remaining tumor cells. However, scanning the patient with an intraoperative probe and applying the treatment are not done simultaneously. In the past we extended the one dimensional signal of a nuclear probe to a four dimensional signal including the spatial information of the distal end of the probe (current status). This signal can be then used to guide the surgeon in the resection of residual tissue and thus increase its spatial accuracy while allowing minimal impact on the patient. The next step is to prepare clinical experiments and integrate the solution into the clinical workflow. The student in charge of this project will contribute in that step by designing ex-vivo and in-vivo experiment protocols, preparing the experimental setup and evaluating the experiments on their own.

Task

Design, preparation and evaluation of experiments (both pre-clinical and clinical). In particular the project will focus on tumor resection in the upper gastrointestinal tract and the control of tumor bed after resection using metabolic radio-tracers and intraoperative nuclear-probes. (For more details see abstract above or live demo at Klinikum rechts der Isar).

Requirements

• Basic knowledge: Surgery, Medical Statistics and some practice in Biology labs (preparation of solutions, etc).
• Recommendable knowledge: Nuclear Medicine and any software for Statistics.
• Interest in technology and advanced research: You will work most of the time at Klinikum rechts der Isar at NaNuLab with a team of physicists, computer scientists and medical engineers. The doctor degree will be developed in parallel with a Diploma thesis of Computer Science.

What you get out of it

• Experience in pre-clinical and clinical trials, and design and evaluation of experiments.
• Experience in Nuclear Medicine and Surgery.
• Experience in an interdiciplinary research team in Medical Technology.
• Knowledge about different fields of research in Technology: Augmented Reality, Computer Graphics, Visualization, Nuclear Imaging, Navigation.
• Loan of a Hiwi (10 to 20 hours a week, definite amount of time to be discussed).

Literature

Z. Jiang, H. Wang, Z. Li, M. Grimm, M. Zhou, U. Eck, S. V. Brecht, T. C. Lueth, T. Wendler, N. Navab
Motion-Aware Robotic 3D Ultrasound
2021 IEEE International Conference on Robotics and Automation (The video is available on youtube)
The first two authors contribute equally to this paper. (bib) A. K. Kogler, A. M. Polemi, S. Nair, S. Majewski, L. T. Dengel, C. L. Slingluff, B. Kross, S. J. Lee, J. E. McKisson^?, J. McKisson^?, A. G. Weisenberger, B. L. Welch, T. Wendler, P. Matthies, J. Traub, M. Witt, M. B. Williams
Evaluation of camera-based freehand SPECT in preoperative sentinel lymph node mapping for melanoma patients
EJNMMI Research 10. https://doi.org/10.1186/s13550-020-00729-8. (bib) C. Cipriani, M. Desantis, G. Dahlhoff, S. D. Brown III, T. Wendler, M. Olmeda, G. Pietsch, B. Eberlein
Personalized irradiation therapy for NMSC by rhenium-188 skin cancer therapy: a long-term retrospective study
J Dermatolog Treat. https://doi.org/10.1080/09546634.2020.1793890 (bib) L. Maier-Hein, I. Gockel, S. Speidel, T. Wendler, D. Teber, K. Maerz, M. Tizabi, F. Nickel, N. Navab, B. Mueller-Stich
Intraoperative Imaging and Visualization
Der Onkologe, volume 26, pages 31 to 43. https://doi.org/10.1007/s00761-019-00695-4 (bib) M. N. van Oosterom, P. Meershoek, , F. Pinto, P. Matthies, H. Simon, T. Wendler, N. Navab, C. J. H. van de Velde, H.G. van der Poel, F.W.B. van Leeuwen
Extending the hybrid surgical guidance concept with freehand fluorescence tomography
IEEE Trans Med Imaging;39(1):226-235. https://doi.org/10.1109/tmi.2019.2924254 (bib) T. Wendler, S. Paepke
Axillary sentinel node aspiration biopsy: towards minimally invasive lymphatic staging in breast cancer
Clinical and Translational Imaging volume 4, pages377–384. https://doi.org/10.1007/s40336-016-0205-8 (bib) A. Markus, A. K. Ray, D. Bolla, J. Müller, P.-A. Diener, T. Wendler, R. Hornung
Sentinel lymph node biopsy in endometrial and cervical cancers using freehand SPECT—first experience
Gynecological Surgery volume 13, pages499–506. https://doi.org/10.1007/s10397-016-0969-x (bib) M. N. van Oosterom, T. Engelen, N. S. van den Berg, G. H. KleinJan^?, H.G. van der Poel, T. Wendler, C. J. H. van de Velde, N. Navab, F.W.B. van Leeuwen
Navigation of a robot-integrated fluorescence laparoscope in preoperative SPECT/CT and intraoperative freehand SPECT imaging data: a phantom study
J Biomed Opt 21(8):86008. https://doi.org/10.1117/1.jbo.21.8.086008 (bib) G. H. KleinJan^?, N. S. van den Berg, M. N. van Oosterom, T. Wendler, M. Miwa, A. Bex, K. Hendricksen, S. Horenblas, F.W.B. van Leeuwen
Toward (Hybrid) Navigation of a Fluorescence Camera in an Open Surgery Setting
J Nucl Med 57(10):1650-1653. https://doi.org/10.2967/jnumed.115.171645 (bib) B. Fuerst, J. Sprung, F. Pinto, B. Frisch, T. Wendler, H. Simon, L. Mengus, N. S. van den Berg, H.G. van der Poel, F.W.B. van Leeuwen, N. Navab
First Robotic SPECT for Minimally Invasive Sentinel Lymph Node Mapping
IEEE Transactions on Medical Imaging, 2015. (bib) O. R. Brouwer, N. S. van den Berg, H. M. Mathéron, T. Wendler, H.G. van der Poel, S. Horenblas, R. A. Valdés-Olmos, F.W.B. van Leeuwen
Feasibility of intraoperative navigation to the sentinel node in the groin using preoperatively acquired single photon emission computerized tomography data: transferring functional imaging to the operating room
J Urol 192(6):1810-6. https://doi.org/10.1016/j.juro.2014.03.127 (bib) A. Cserkaszky, M. Zvolsky, B. Frisch, T. Wendler
Simulation Framework for Novel Medical Applications
IEEE Nuclear Science Symposium and Medical Imaging Conference, Seattle, USA, November 2014 (bib) A. Okur, C. Hennersperger, J.B. Runyan, J. Gardiazabal, M. Keicher, S. Paepke, T. Wendler, N. Navab
fhSPECT-US Guided Needle Biopsy of Sentinel Lymph Nodes in the Axilla: Is it Feasible?
Medical Image Computing and Computer-Assisted Intervention, MICCAI 2014, Lecture Notes in Computer Science Volume 8673, 2014, pp 577-584 (bib) A. Okur, C. Gerngross, A. Schnelzer, A. Ehlerding, M. Keicher, S. Wiesner, S. Paepke, K. Scheidhauer, T. Wendler
First experience with fused ultrasound / freehand SPECT system for hybrid lymphatic mapping in breast cancer patients
52. Jahrestagung der Deutschen Gesellschaft fuer Nuklearmedizin, Hannover, Germany, Mar. 26 - 29, 2014. (bib) P. Matthies, A. Okur, T. Wendler, N. Navab, M. Friebe
Combination of intra-operative freehand SPECT imaging with MR images for guidance and navigation
IEEE Engineering in Medicine and Biology (EMBC), Osaka, Japan, July 2013. (bib) N. Aubry, E. Auffray, F. B. Mimoun, N. Brillouet, R. Bugalho, , O. Charles, D. Cortinovis, P. Courday, A. Cserkaszky, C. Damon, K. Doroud, J.-M. Fischer, G. Fornaro, J.-M. Fourmigue, B. Frisch, B. Fuerst, J. Gardiazabal, K. Gadow, E. Garutti, C. Gaston, A. Gil-Ortiz, E. Guedj, T. Harion, P. Jarron, J. Kabadanian, T. Lasser, R. Laugier, P. Lecoq, D. Lombardo, S. Mandai, E. Mas, T. Meyer, O. Mundler, N. Navab, C. Ortigão, M. Paganoni, D. Perrodin, M. Pizzichemi, J. O. Prior, T. Reichl, M. Reinecke, M. Rolo, H.-C. Schultz-Coulon, M. Schwaiger, W. Shen, A. Silenzi, J. C. Silva, , I. Somlai-Schweiger, R. Stamen, J. Traub, J. Varela, V. Veckalns, V. Vidal, J. Vishwas, T. Wendler, C. Xu, S. I. Ziegler, M. Zvolsky
EndoTOFPET-US: a novel multimodal tool for endoscopy and positron emission tomography
JINST 8 C04002. https://doi.org/10.1088/1748-0221/8/04/C04002 (bib) A. Rieger, J. Saeckl, R. Hein, A. Okur, T. Wendler, K. Scheidhauer, T. Schuster, H. Friess, M. E. Martignoni
Transferring Innovative Freehand SPECT to the Operating Room - First Experiences with Sentinel Lymphonodectomy in Malignant Melanoma
32nd Congress of the European Society of Surgical Oncology, Valencia, Spain, September 2012 (bib) N. Navab, T. Blum, L. Wang, A. Okur, T. Wendler
First Deployments of Augmented Reality in Operating Rooms
IEEE Computer, Volume 45, Issue 7, pp. 48-55 (bib) M. Friebe, T. Wendler, J. Traub, B. Tombach, N. Navab
3D handheld SPECT combined with serially acquired MRI reference images - feasibility study for intraoperative applications
Proceedings of the 9th Interventional MRI Symposium Boston, September 2012 (bib) C. Vetter, T. Lasser, T. Wendler, N. Navab
1D-3D Registration for Functional Nuclear Imaging
Medical Image Computing and Computer Assisted Intervention (MICCAI), Toronto, Canada, September 20-24 2011. (bib) A. Okur, A. Ahmadi, A. Bigdelou, T. Wendler, N. Navab
MR in OR: First analysis of AR/VR visualization in 100 intra-operative Freehand SPECT acquisitions
The 10th IEEE and ACM International Symposium on Mixed and Augmented Reality (ISMAR), Basel, Switzerland, Oct. 26 - 29, 2011. (bib) A. Bigdelou, T. Sterner, S. Wiesner, T. Wendler, F. Matthes, N. Navab
OR Specific Domain Model for Usability Evaluations of Intra-Operative Systems
Information Processing in Computer Assisted Interventions (IPCAI), Berlin (DE), June 22, 2011 (bib) A. Rieger, J. Saeckl, B. Belloni, R. Hein, A. Okur, K. Scheidhauer, T. Wendler, J. Traub, H. Friess, M. E. Martignoni
First Experiences with Navigated Radio-Guided Surgery Using Freehand SPECT
Case Reports in Oncology, August 2011 (bib) C. Lapa, J. Saeckl, A. Rieger, C. Bluemel, A. Okur, T. Wendler, M. E. Martignoni, K. Scheidhauer
Investigating added value of freehand SPECT in sentinel node biopsy of melanomas
Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), San Antonio, Texas, USA, June 2011 (bib) C. Bluemel, A. Ehlerding, C. Lapa, A. Okur, T. Wendler, A. Schnelzer, K. Scheidhauer
Improvements in sentinel node biopsy of breast cancer using freehand SPECT
Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), San Antonio, Texas, USA, June 2011 (bib) T. Wendler, T. Lasser, S. I. Ziegler, K. Scheidhauer
Freehand SPECT/US: new approach for intraoperative hybrid imaging of sentinel nodes
Proceedings of the International Sentinel Node Society Meeting, Yokohama, Japan, 2010 (bib) T. Wendler, D. Zaeuner, S. Wiesner, K. Scheidhauer
Fused SPECT/CT and real-time video visualization for intraoperative guidance in SLNB of head and neck malignancies
Proceedings of the International Sentinel Node Society Meeting, Yokohama, Japan, 2010 (bib) K. Scheidhauer, A. Ehlerding, J. Saeckl, A. Rieger, K. Herrmann, A. Schnelzer, M. E. Martignoni, T. Wendler
Feasibility evaluation of freehand SPECT for intraoperative 3D lymphatic mapping
Proceedings of the International Sentinel Node Society Meeting, Yokohama, Japan, 2010 (bib) I. Santi, L. Fantini, K. Herrmann, Ch. Fuccio, T. Wendler, P. Caroli, P. Castelucci, S. Nicolini, A. K. Buck, M. Schwaiger, S. Fanti
Freehand SPECT 3D-imaging for sentinel lymph node mapping in breast cancer: preliminary preoperative study for future intraoperative use in the operating room
Proceedings of the International Sentinel Node Society Meeting, Yokohama, Japan, 2010 (bib) M. C. Kreissl, T. Wendler, K. Herrmann, K. Scheidhauer
Freehand SPECT: First experiences with a new method of 3D-SLN mapping in melanoma
Proceedings of the International Sentinel Node Society Meeting, Yokohama, Japan, 2010 (bib) I. Santi, L. Fantini, K. Herrmann, Ch. Fuccio, T. Wendler, P. Caroli, P. Castelucci, A. K. Buck, M. Schwaiger, S. Fanti
Freehand SPECT for sentinel lymph node biopsy: first clinical experience
Proceedings of EANM 2010, Vienna, Austria, October 2010 (bib) A. K. Buck, A. Ehlerding, J. Saeckl, K. Herrmann, T. Wendler, M. E. Martignoni, A. Schnelzer, M. Schwaiger
Evaluation of feasibility of freehand SPECT in the operating room
Proceedings of EANM 2010, Vienna, Austria, October 2010 (bib) A. Schnelzer, A. Ehlerding, T. Chen, T. Wendler, K. Scheidhauer, S. Paepke, M. Kiechle
Sentinel lymph node detection with intraoperative freehand SPECT in breast cancer patients
Proceedings of the Annual Meeting of the German Society of Gynecology and Obstetrics (DGGG) 2010, Munich, Germany, October 2010 (bib) A. Ehlerding, A. Schnelzer, T. Wendler, K. Herrmann, T. Lasser, K. Scheidhauer, O. Kutter, T. Schuster, M. Schwaiger, A. K. Buck, S. I. Ziegler, N. Navab, S. Paepke, M. Kiechle
Vorstellung der Pilotstudie zur 3D-Darstellung des Wächterlymphknotens bei Brustkrebspatientinnen mittels Freehand-SPECT
Proceedings of Annual Meeting of the German Society of Senology (DGS), Hamburg, Germany, Jul. 2010 (bib) T. Wendler, K. Herrmann, A. Schnelzer, M. E. Martignoni, T. Lasser, J. Traub, A. Ehlerding, J. Saeckl, N. Navab, M. Kiechle, H. Friess, M. Schwaiger, S. I. Ziegler, A. K. Buck
Visione 3-D SPECT intraoperatoria: una nuova metodica per chirurgia radioguiata
Proceedings of SICO 2010, Milan, Italy, June 2010 (bib) I. Santi, L. Fantini, K. Herrmann, Ch. Fuccio, T. Wendler, P. Caroli, P. Castelucci, A. K. Buck, M. Schwaiger, S. Fanti
Freehand SPECT for sentinel lymph node biopsy: first clinical experience
Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), Salt Lake City, Utah, USA, June 2010 (bib) D. I. Shakir, J. Bieniarz, S. Pirsig, T. Wendler, N. Navab, S. I. Ziegler
A first study on biological feasibility of intraoperative control of tumor resection borders with navigated beta-probe surface imaging
Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), Salt Lake City, UT, USA, June 2010 (bib) M. C. Kreissl, A. Okur, T. Chen, A. Bartel, T. Wendler, K. Scheidhauer
Pilot study of freehand SPECT for lymphatic mapping in melanoma in upper body
Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), Salt Lake City, Utah, USA, June 2010 (bib) K. Herrmann, A. Schnelzer, M. E. Martignoni, T. Wendler, A. K. Buck
Evaluation of feasibility of freehand SPECT in the operating room
Proceedings of the Annual Meeting of the Society of Nuclear Medicine (SNM), Salt Lake City, Utah, USA, June 2010 (bib) T. Wendler, K. Herrmann, A. Schnelzer, T. Lasser, J. Traub, O. Kutter, A. Ehlerding, K. Scheidhauer, T. Schuster, M. Kiechle, M. Schwaiger, N. Navab, S. I. Ziegler, A. K. Buck
First Demonstration of 3D Lymphatic Mapping using freehand SPECT
Proceedings of the International Conference on Sentinel Node Biopsy and Radioguided Head & Neck Surgery (SNB), Copenhagen, Denmark, May 2010 (bib) J. Saeckl, A. Ehlerding, K. Herrmann, T. Wendler, M. Schwaiger, M. Kiechle, H. Friess, A. K. Buck, A. Schnelzer, M. E. Martignoni
Evaluation of feasibility of freehand SPECT in the operating room
Proceedings of the International Conference on Sentinel Node Biopsy and Radioguided Head & Neck Surgery (SNB), Copenhagen, Denmark, May 2010 (bib) A. K. Buck, A. Schnelzer, T. Wendler, K. Herrmann, T. Lasser, J. Traub, O. Kutter, T. Schuster, A. Ehlerding, K. Scheidhauer, M. Kiechle, N. Navab, S. I. Ziegler, M. Schwaiger
First demonstration of 3D lymphatic mapping in breast cancer using freehand SPECT
Proceedings of DGN Nuklearmedizin 2010, Leipzig, Germany, April 2010 (bib) K. Herrmann, A. Schnelzer, T. Wendler, M. Hoyer, D. Weisgerber, T. Lasser, S. Paepke, M. E. Martignoni, M. Kiechle, N. Navab, S. I. Ziegler, M. Schwaiger
Evaluation of feasibility of freehand SPECT in the operating room
Proceedings of DGN Nuklearmedizin 2010, Leipzig, Germany, April 2010 (bib) T. Wendler, K. Herrmann, A. Schnelzer, T. Lasser, J. Traub, O. Kutter, A. Ehlerding, K. Scheidhauer, T. Schuster, M. Kiechle, M. Schwaiger, N. Navab, S. I. Ziegler, A. K. Buck
First demonstration of 3-D lymphatic mapping in breast cancer using freehand SPECT
European Journal of Nuclear Medicine and Molecular Imaging, Springer Berlin/Heidelberg, 2010 Aug;37(8):1452-61. Epub 2010 Mar 31. (bib) A. Duliu, T. Lasser, T. Wendler, A. Safi, S. I. Ziegler, N. Navab
Navigated Tracking of Skin Lesion Progression with Optical Spectroscopy
Proceedings of SPIE Vol. 7624, 76243P (2010) (bib) J. Traub, K. Herrmann, T. Lasser, N. Navab, S. I. Ziegler, A. K. Buck, T. Wendler
Freehand SPECT/Ultrasound Fusion for Hybrid Image-guided Resection
Proceedings of RSNA 2009, Chicago, USA, December 2009 (bib) T. Wendler, K. Herrmann, A. Schnelzer, T. Lasser, J. Traub, O. Kutter, T. Schuster, M. Kiechle, M. Schwaiger, N. Navab, S. I. Ziegler, A. K. Buck
Clinical introduction of freehand SPECT for image-guided sentinel lymph node biopsy
Proceedings of Annual Congress of the European Association of of Nuclear Medicine (EANM 2009), Barcelona, Spain, October 2009 (bib) T. Wendler, X. Feng, K. Herrmann, T. Lasser, J. Traub, S. I. Ziegler, N. Navab, A. K. Buck
2D/3D registration of freehand SPECT and planar scintigraphy for clinical evaluation of 3D thyroid scintigraphy
Proceedings of Annual Congress of the European Association of of Nuclear Medicine (EANM 2009), Barcelona, Spain, October 2009 (bib) T. Wendler, K. Herrmann, T. Lasser, J. Traub, M. Schwaiger, N. Navab, S. I. Ziegler, A. K. Buck
First experience with freehand SPECT for lymphatic mapping in melanoma in upper body
Proceedings of Annual Congress of the European Association of of Nuclear Medicine (EANM 2009), Barcelona, Spain, October 2009 (bib) T. Wendler, T. Lasser, J. Traub, S. I. Ziegler, N. Navab
Freehand SPECT / ultrasound fusion for hybrid image-guided resection
Proceedings of Annual Congress of the European Association of of Nuclear Medicine (EANM 2009), Barcelona, Spain, October 2009 (bib) T. Lasser, A. Duliu, T. Wendler, S. I. Ziegler, N. Navab
Interactive Reconstruction for Freehand SPECT: An Approach to Acquisition Guidance?
Proceedings of Annual Congress of the European Association of of Nuclear Medicine (EANM 2009), Barcelona, Spain, October 2009 (bib) C. Özgür, J. Bieniarz, T. Lasser, S. I. Ziegler, N. Navab, T. Wendler
Phenomenological Models for intraoperative Positron Emission Surface Imaging using Handheld Probes
Proceedings of World Congress in Medical Physics and Biomedical Engineering (WC 2009), Munich, Germany, September 2009 (bib) X. Feng, K. Szajkowska, T. Lasser, S. I. Ziegler, N. Navab, T. Wendler
2D/3D registration of freehand SPECT and planar scintigraphy for clinical evaluation of 3D thyroid scintigraphy
Proceedings of World Congress in Medical Physics and Biomedical Engineering (WC 2009), Munich, Germany, September 2009 (bib) J. Traub, K. Herrmann, T. Wendler, T. Lasser, M. Schwaiger, N. Navab, S. I. Ziegler, A. K. Buck
First clinical results of freehand SPECT for lymphatic mapping in breast cancer
Proceedings of the Molekulare Bildgebung (MOBI), Berlin, Germany, Jun. 2009 (bib) T. Wendler, K. Herrmann, T. Lasser, J. Traub, M. Schwaiger, S. I. Ziegler, N. Navab, A. K. Buck
Freehand SPECT: first in-vivo evaluation and comparison to conventional lymphatic mapping
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2009), Toronto, Canada, June 2009 (bib) T. Wendler, X. Feng, T. Lasser, K. Herrmann, J. Traub, K. Scheidhauer, S. I. Ziegler, D. Lenhart, J. Grahneis, M. Schwaiger, N. Navab, A. K. Buck
Freehand SPECT for 3D thyroid scintigraphy: first patient report
Proceedings of DGN Nuklearmedizin 2009, Leipzig, Germany, April 2009 (bib) K. Herrmann, T. Wendler, T. Chen, A. Bartel, T. Lasser, K. Scheidhauer, J. Traub, T. Schuster, S. I. Ziegler, M. Schwaiger, A. K. Buck, N. Navab
Freehand SPECT: first in-vivo use for lymphatic mapping and comparison to conventional imaging
Proceedings of DGN Nuklearmedizin 2009, Leipzig, Germany, April 2009 (bib) T. Wendler, T. Lasser, A. K. Buck, C. Özgür, M. Schwaiger, S. I. Ziegler, N. Navab
First in Vivo Use of a Fused Gamma Ultrasound System
Proceedings of RSNA 2008, Chicago, USA, December 2008 (bib) T. Wendler, T. Lasser, S. I. Ziegler, N. Navab
Towards Confident 3D Tomographic Reconstruction for Asymmetric, Sparse Detector Geometries
Proceedings of IEEE Medical Imaging Conference (IEEE MIC 2008), Dresden, Germany, October 2008 (bib) T. Lasser, T. Wendler, S. I. Ziegler, N. Navab
Towards Reproducibility of Freehand 3D Tomographic Nuclear Imaging
Proceedings of IEEE Medical Imaging Conference (IEEE MIC 2008), Dresden, Germany, October 2008 (bib) T. Lasser, T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Definition of optimal collimator geometries for 3D tomographic thyroid scintigraphy using navigated gamma probes
Proceedings of Annual Congress of the European Association of Nuclear Medicine (EANM 2008), Munich, Germany, October 2008 (bib) T. Wendler, T. Lasser, A. K. Buck, J. Traub, M. Schwaiger, S. I. Ziegler, N. Navab
First case report of 3D tomographic thyroid scintigraphy with tracked gamma probes
Proceedings of Annual Congress of the European Association of Nuclear Medicine (EANM 2008), Munich, Germany, October 2008, Eur J Nuc Med Mol Imaging, vol. 35 (Suppl. 2), S129 (bib) T. Wendler, A. Hartl, T. Lasser, J. Traub, S. I. Ziegler, N. Navab
Tracking-based statistical correction for radio-guided cancer surgery
Proceedings of World Molecular Imaging Congress (WMIC 2008), Nice, France, September 2008 (bib) T. Lasser, A. Duliu, T. Wendler, J. Becker, S. I. Ziegler, N. Navab
Computer-assisted spectral quantification of disease progression in CTCL
Proceedings of World Molecular Imaging Congress (WMIC 2008), Nice, France, September 2008 (bib) T. Wendler, J. Traub, T. Lasser, M. Feuerstein, J. Vogel, S. I. Ziegler, N. Navab
Combined ultrasound and gamma probe imaging for examination of thyroid nodules
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib) T. Wendler, A. Hartl, T. Lasser, J. Traub, S. I. Ziegler, N. Navab
3D Intra-operative nuclear imaging for SLNB in neck
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib) T. Lasser, A. Duliu, T. Wendler, S. I. Ziegler, N. Navab
Navigated tracking of skin lesion progression with optical spectroscopy
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib) A. Hartl, T. Wendler, J. Traub, T. Lasser, S. I. Ziegler, N. Navab
Confident radioactivity surface reconstruction for control of resection borders
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2008), New Orleans, USA, June 2008 (bib) N. Navab, J. Traub, A. K. Buck, S. I. Ziegler, T. Wendler
Navigated nuclear probes for intra-operative functional imaging
Proceedings of 5th IEEE International Symposium on Biomedical Imaging (ISBI 2008), Paris, France, May 14 - 17 2008, pp. 1395-1398 (bib) T. Wendler, I. Faure de Pebeyre, T. Lasser, N. Navab
Integrated Surface Acquisition for Hand-Held Probes
Proceedings of OSA Biomedical Optics (BIOMED 2008), St. Petersburg, USA, March 2008 (bib) T. Wendler, M. Feuerstein, J. Traub, T. Lasser, J. Vogel, F. Daghighian, S. I. Ziegler, N. Navab
Real-time fusion of ultrasound and gamma probe for navigated localization of liver metastases
Proceedings of Medical Image Computing and Computer-Assisted Intervention (MICCAI 2007), Brisbane, Australia, October 29 - November 2007, LNCS 4792 (2), pp. 909-917 (bib) T. Wendler, A. Hartl, T. Lasser, J. Traub, F. Daghighian, S. I. Ziegler, N. Navab
Towards intra-operative 3D nuclear imaging: reconstruction of 3D radioactive distributions using tracked gamma probes
Proceedings of Medical Image Computing and Computer-Assisted Intervention (MICCAI 2007), Brisbane, Australia, October 29 - November 2 2007, LCNS 4792 (2), pp. 252-260 (bib) A. Hartl, T. Wendler, T. Lasser, J. Traub, S. I. Ziegler, N. Navab
Towards intra-operative 3D nuclear imaging: development and evaluation of ad hoc models
Proceedings of Jahrestagung der deutschen Gesselschaft für Computer- und Roboterassistierte Chirurgie e.V. (CURAC 2007), Karlsruhe, Germany, October 2007 (bib) T. Wendler, J. Traub, A. Hartl, T. Lasser, M. Burian, A. K. Buck, F. Daghighian, M. Schwaiger, S. I. Ziegler, N. Navab
Adding navigation to radio-guided surgery: new possibilities, new problems, new solutions
Proceedings of Russian Bavarian Conference on Biomedical Engineering (RBC Biomed 2007), Erlangen, Germany, July 2-3, 2007, pp. 96-100 (bib) T. Wendler, A. Hartl, J. Traub, S. I. Ziegler, N. Navab
Intraoperative nuclear imaging using navigated gamma-probes for tumor localization
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2007), Washington D.C., USA, June 2007 (bib) T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Validation of navigated beta-probe imaging with PET/CT-generated activity surfaces. New approach in radio-guided resection for FDG-positive tumors
Proceedings of Annual Meeting of Society of Nuclear Medicine (SNM 2007), Washington D.C., USA, June 2007; Meeting Abstracts 48: 46P-b. (bib) O. Kishenkov, T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Method for projecting functional 3D information onto anatomic surfaces: Accuracy improvement for navigated 3D beta-probes
Proceedings of Bildverarbeitung fuer die Medizin (BVM 2007), Munich, Germany, March 2007, pp.66-70 (bib) T. Wendler, J. Traub, S. I. Ziegler, N. Navab
Navigated three dimensional beta probe for optimal cancer resection
Proceedings of Medical Image Computing and Computer-Assisted Intervention (MICCAI 2006), Copenhagen, Denmark, October 1-6 2006, LNCS 4190 (1), pp. 565-569 (bib)

Contact

If you are interested in this project, please send an email to Joerg Traub (traub@cs.tum.edu). Alternative projects in the field of medical navigation systems and augmented reality visualization are available on request.